Abnormalities in overall growth regulation are likely involved in congenital cardiovascular disease The poor growth observed in children born with complex heart defects might result from factors beyond deficient nutrition levitra online . A new study by pediatric experts suggests that abnormalities in overall growth regulation play a role. When compared with their healthy peers, children with congenital cardiovascular disease have impaired growth, as measured in pounds, length, and mind circumference, said senior writer Meryl S. Cohen, M.D., a pediatric cardiologist in the Cardiac Middle at The Children's Hospital of Philadelphia. We investigated patterns of poor development in these children, as a starting place in guiding us toward more effective remedies.
In the September 7 The research appears, 2011, issue of the journal Science Translational Medicine. Hydrocephalus, which involves excessive buildup of cerebrospinal fluid in the brain, impacts about 1 in 500 kids in the United States. Currently only symptomatic treatment exists-the surgical keeping a shunt to drain away excess fluid. Researchers wish to know the condition’s causes, so they can work out how to prevent and treat it. Scientists have known for quite a while that hydrocephalus was linked to bleeding events in the developing brain, but the reason behind that linkage is not clear. The brand new study now shows that hydrocephalus can be triggered by irregular degrees of lysophosphatidic acid , a blood-borne lipid that may enter the brain in high concentrations during bleeding events, with profound results on developing human brain cells.