Shapiro, M.D., M.P.H., M.D. Hughes, Ph.D., A. Ogwu, M.B., B.S., D. Kitch, M.S., S. Lockman, M.D., C. Moffat, M.B., Ch.B., M.P.H., J. Makhema, M.B., Ch.B., M.R.C.P., S. Moyo, M.P.H., I. Thior, M.D., K. McIntosh, M.D., E. Van Widenfelt, B.S., J. Leidner, M.S., K. Powis, M.D., M.P.H., A. Asmelash, M.D., M.P.H., E. Tumbare, M.B., Ch.B., S. Zwerski, M.S.N., U. Sharma, Ph.D., M.P.H., E. Handelsman, M.D., K. Mburu, B.Pharm., O. Jayeoba, M.B., Ch.B., E. Moko, M.B., Ch.B., S. Souda, M.D., E. Lubega, M.D., M. Akhtar, M.B., Ch.B., C. Wester, M.D., M.P.H., R. Tuomola, M.D., W. Snowden, Ph.D., M. Martinez-Tristani, M.D., L. Mazhani, M.D., and M. Essex, D.V.M., Ph.D.: Antiretroviral Regimens in Breast-Feeding and Pregnancy in Botswana Highly active antiretroviral therapy used to prevent in utero and intrapartum mother-to-child transmission of human immunodeficiency virus type 1 has become the successful public health interventions of the HIV era.1,2 However, the usage of HAART in mothers to prevent mother-to-child transmitting through breast-feeding in regions of the globe where replacement feeding is neither safe and sound nor feasible continues to be an unproven strategy.1,3 We compared different HAART regimens found in pregnancy and during breast-feeding to determine whether the regimens differ regarding virologic suppression during pregnancy and breast-feeding, pregnancy outcomes, and toxic effects in mothers and infants.Despite the stress and hard work involved, 77 per cent of Canadians estimate that they can smile a lot more than 10 times when entertaining family and friends this holiday season. Keeping that holiday smile white and shiny can be challenging during the holidays with the excessive food, cheer and drink. ‘When it comes to teeth-staining holiday indulgences like burgandy or merlot wine, chocolate and coffee, 91 per cent of Canadians state they won’t avoid them this season,’ said Court Elliott, Communications Supervisor, Philips Canada.