Cross posted from Nature’s THE FANTASTIC Beyond blog page. Long derided by a lot of the mainstream medical community, acupuncture may have simply got a little bit less alternative. Despite a large number of years of anecdotal evidence claiming benefits in dealing with ailments from allergy symptoms to hiccups, acupuncture faces two big challenges to acceptance in mainstream medicine: most medical trials have found no evidence of efficacy; and there is absolutely no scientifically accepted mechanism for how the treatment could work. Many researchers presume that any benefits are down to the placebo effect. Read the remaining post on The Great Beyond. Image by peruisay via Flickr Innovative Commons.All the individuals subsequently received ticagrelor at a dose of 90 mg twice daily for 30 days, with a suggestion that treatment be continuing for a complete of 12 months. In-ambulance usage of glycoprotein IIb/IIIa inhibitors was discouraged but was remaining to the physician’s discretion. In-laboratory usage of glycoprotein IIb/IIIa inhibitors after angiography needed to be determined as the strategy of choice or a bailout treatment during PCI. A pharmacodynamic substudy was executed at five participating centers, the primary end point which was the result of a phosphorylation assay for calculating the platelet-reactivity index of a vasodilator-stimulated phosphoprotein in the beginning of catheterization .25 Study End Points The coprimary end points were the proportion of patients who didn’t have 70 percent or greater resolution of ST-segment elevation before PCI and the proportion of patients who did not meet the requirements for TIMI flow grade 3 in the infarct-related artery at angiography before PCI.