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People with CLI face a higher threat of amputation and, in some full cases, death. Approximately 1 million people in the U.S. Have problems with CLI, which results in a lot more than 160,000 amputations each full year. Related StoriesInner ear damage mind warnings from nerve cellsHPV analysis partnership signed between Beckman Coulter and IncellDxJumping genes: a marker for early cancer medical diagnosis? An interview with Dr Kazazian Aastrom’s RESTORE-CLI trial may be the largest double-blind, randomized cell therapy study becoming conducted for CLI. The trial provides enrolled a total of 86 sufferers at 18 sites in the usa. Patients in the procedure group received intramuscular shots of TRCs into the affected limb, while control sufferers received intramuscular injections with an electrolyte solution .